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Adenosine Half Life. Data regarding the clearance of adenosine are not readily available. The maximal plasma concentration of regadenoson is achieved within 1 to 4 minutes after injection and parallels the onset of the pharmacodynamic response.
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Treatment of any prolonged adverse effects should be individualized and be directed toward the specific effect. Adenosine is used to help restore normal heartbeats in people with certain heart rhythm disorders. There are two important metabolic fates for adenosine.
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Phosphorylation, via adenosine kinase, allows adenosine to be further metabolized as cellular energy while deamination occurs by adenosine deaminase, eventually forming. Wall motion abnormality during adenosine infusion and found that most did not develop a wall motion abnormality despite the development of a thallium defect. The usual infusion lasts 6 minutes. Administration of iv aminophylline or theophylline may be needed.